Anti–β2-Glycoprotein I and Antiphosphatidylserine Antibodies Are Predictors of Arterial Thrombosis in Patients With Antiphospholipid Syndrome
نویسندگان
چکیده
منابع مشابه
Prevalence of Antiphospholipid Antibodies in Syrian Patients with Thrombosis
Background: Antiphospholipid antibodies (aPL) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. Objective: To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. Methods: One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (...
متن کاملAntibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with ‘seronegative’ antiphospholipid syndrome
The standard serological tests included in the classification criteria for antiphospholipid syndrome (APS) are those to detect immunoglobulin G (IgG) and IgM antibodies to cardiolipin (aCL) or β-2-glycoprotein I (anti-β2GPI) and the lupus anticoagulant. It is increasingly recognised, however, that some patients have typical thrombotic and non-thrombotic features of APS but test repeatedly negat...
متن کاملAnti-beta 2-glycoprotein I, antiprothrombin antibodies, and the risk of thrombosis in the antiphospholipid syndrome.
The association of antiphospholipid antibodies with thrombosis and obstetric events defines the antiphospholipid syndrome. A recent systematic review of the literature showed lupus anticoagulants to be risk factors of thrombosis, independent of the type and site of the event, the presence of systemic lupus erythematosus, and the laboratory methods used to detect them. Anticardiolipin antibodies...
متن کاملprevalence of antiphospholipid antibodies in syrian patients with thrombosis
background: antiphospholipid antibodies (apl) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. objective: to study the prevalence of apl in patients with thrombosis at aleppo university hospitals, syria. methods: one hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. anticardiolipin antibodies (...
متن کاملHigh avidity anti-b2-glycoprotein I antibodies in patients with antiphospholipid syndrome
Objective: To evaluate avidity of IgG anti-b2-glycoprotein I antibodies (anti-b2-GPI) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) in relation to thrombosis, and to demonstrate a possible affinity maturation of IgG anti-b2-GPI during the disease course. Methods: 64 sera from 32 patients (18 with primary or secondary APS, 14 with SLE without APS) and th...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2004
ISSN: 0002-9173,1943-7722
DOI: 10.1309/yvq6px76xmym3j29